|
Dyslipidemias
|
0.400 |
AlteredExpression
|
group |
BEFREE |
We explore the effects of sex; educational level; socioeconomic status; residence area; occupation type; marital status; history of hypertension, diabetes mellitus, and dyslipidemia; tobacco and alcohol use; and APOE ε4 on the rates of cognitive decline.
|
26902171 |
2016 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
Residues Leu261, Trp264, and Phe265 account for apolipoprotein E-induced dyslipidemia and affect the formation of apolipoprotein E-containing high-density lipoprotein.
|
17655277 |
2007 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
Such findings support the active role of placental LPL and APOE in the metabolism of maternal lipoproteins and suggest that fetal genes may modulate the risk for problems related to maternal dyslipidemia (preeclampsia, pancreatitis, and future cardiovascular disease).
|
16106048 |
2005 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
Only APOE*4 conferred a risk against longevity and was associated with high-cholesterol (hTC) and mixed dyslipidemia for oldest-old females.
|
24746514 |
2014 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
Apolipoprotein E (apo E) deficiency (or its abnormalities in humans) is associated with a series of pathological conditions including dyslipidemia, atherosclerosis, Alzheimer's disease, and shorter life span.
|
11726538 |
2001 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
Dyslipidemia in LPG generally resembles type III hyperlipoproteinemia with elevated serum apolipoprotein E level.
|
30685233 |
2020 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
In this study, we investigate the lipid composition in the plasma of apolipoprotein E deficient (ApoE<sup>-/-</sup>) mice fed a high-fat diet to reveal atherosclerosis-induced dyslipidemia.
|
28527370 |
2017 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
We have previously shown that MGL affects plaque stability in apolipoprotein E (ApoE)-/- mice, an established animal model for dyslipidemia and atherosclerosis.
|
28380440 |
2017 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
The present study indicates that in the Ouro Preto admixed population the presence of APOE *2 can confer a protective effect, whereas the presence of APOE *4 implies an enhanced risk for dyslipidemia.
|
17224996 |
2007 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
CTD_human |
Adiponectin expression and the cardioprotective role of the vitamin D receptor activator paricalcitol and the angiotensin converting enzyme inhibitor enalapril in ApoE-deficient mice.
|
25037058 |
2014 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
This study aimed to investigate CF dyslipidaemia, its clinical correlates and links to oxidized low-density lipoprotein (oxLDL), adiponectin, and apolipoprotein E (APOE).
|
30979683 |
2019 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
Apolipoprotein E (apo E), a genetic determinant of plasma lipid levels and coronary heart disease (CHD) needs to be investigated in Asian Indians since they have a propensity to develop dyslipidemia and accelerated atherosclerosis.
|
12030385 |
2002 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
While both quantitative and qualitative changes of apoE are established causes of rare dyslipidemia syndromes, it remains unclear whether plasma levels of apoE are associated with risk of IHD in the general population.
|
26761769 |
2016 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
We evaluated predictors including demographics, APOE, intellectual enrichment, midlife risk factors (physical inactivity, obesity, smoking, diabetes, hypertension, and dyslipidemia), and the total number of late-life cardiac and metabolic conditions.
|
28418521 |
2017 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
In our current study, we have examined the effects of long-term feeding of a 1,3-DAG-rich oil on the dyslipidemia and atherosclerosis in the experimental model of the diabetic apolipoprotein E (apoE)-deficient mouse that develops accelerated atherosclerosis.
|
16996521 |
2007 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
APOE and LDLR Gene Polymorphisms and Dyslipidemia Tracking. Rio de Janeiro Study.
|
26131702 |
2015 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
Green tea polyphenol treatment attenuates atherosclerosis in high-fat diet-fed apolipoprotein E-knockout mice via alleviating dyslipidemia and up-regulating autophagy.
|
28777810 |
2017 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
Activation of renin-angiotensin system is involved in dyslipidemia-mediated renal injuries in apolipoprotein E knockout mice and HK-2 cells.
|
23570453 |
2013 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
LHGDN |
The present study indicates that in the Ouro Preto admixed population the presence of APOE *2 can confer a protective effect, whereas the presence of APOE *4 implies an enhanced risk for dyslipidemia.
|
17224996 |
2007 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
The specific aims of current study included to clarify lipidomic perturbation in liver tissues of apolipoprotein E deficient (apoE<sup>-/-</sup>) mice fed with high-fat diet, and to examine the effects of rhodioloside against atherosclerosis and dyslipidemia.
|
30389273 |
2018 |
|
Dyslipidemias
|
0.400 |
Biomarker
|
group |
BEFREE |
APOB, APOC3, and APOE and apolipoprotein-defined lipoprotein subclasses (ADLSs; based on qualitative apolipoprotein complement) have been associated with dyslipidemia and CVD.
|
31203233 |
2019 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
To better inform prevention, future consideration should be given toward managing dyslipidemia in women carrying the APOE ɛ4 allele.
|
30689578 |
2019 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
ApoE4 allele is associated with obesity independent of dyslipidemia in women but not men with a family history of diabetes.
|
11553047 |
2001 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
A similar phenotype of combined dyslipidemia was induced in apoE(-/-) or apoE(-/-) x LDLr(-/-) mice after infection with a low dose (4 x 10(8) pfu) of an adenovirus expressing the apoE4[R142V/R145V] mutant previously shown to be defective in receptor binding.
|
16339113 |
2006 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Further screening for common apoE gene variants in individuals at risk for dyslipidemia may reveal abnormal heteroduplex patterns and uncover further mutations in this important lipid-regulating gene.
|
15514092 |
2005 |